Article
Biochemical activities associated with mouse Mcm2 protein.
The Journal of biological chemistry - 16 Nov 2001
Ishimi Y, Komamura-Kohno Y, Arai K, Masai H
Abstract excerpt
Mcm2, a member of the Mcm2-7 protein family essential for the initiation of DNA replication, has several biochemical activities including the ability to inhibit the Mcm4,6,7 helicase. In this study, we characterized the activities associated with Mcm2 and determined the region required for them. It was found that Mcm2 deleted at an amino-terminal portion is able to bind to an Mcm4,6,7 hexameric complex and to...
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