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Article

Presence of telomeric G‐strand tails in the telomerase catalytic subunit <i>TERT</i> knockout mice

1 Oct 1999

Abstract excerpt

BACKGROUND: Telomerase consists of two essential subunits, the template RNA (TR; telomerase RNA) and the catalytic subunit TERT (telomerase reverse transcriptase). Knockout mice with a mTR (mouse TR) deletion have been described and well characterized. However, mice with a mTERT (mouse TERT) deletion have not been reported. RESULTS: mTERT-knockout mice have been constructed. The first generation mTERT -/- mice...

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PMID: 10583505
DOI: 10.1046/j.1365-2443.1999.00284.x

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