Article
Cdx1 promotes differentiation in a rat intestinal epithelial cell line.
Gastroenterology - 1 Dec 1999
Soubeyran P, André F, Lissitzky J C, Mallo G V, Moucadel V, Roccabianca M, Rechreche H, Marvaldi J, Dikic I, Dagorn J C, Iovanna J L
Abstract excerpt
BACKGROUND & AIMS: Homeobox genes are involved in establishing and maintaining differentiated patterns in adult tissues. Cdx1 might carry out that function in the intestinal epithelium because its expression is specific to that tissue and increases during development. METHODS: Cdx1 expression was induced in IEC-6 intestinal epithelial cells by stable transfection, and subsequent changes in cell growth, resistance...
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