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Article

Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jun 1999

Beck F, Chawengsaksophak K, Waring P, Playford R J, Furness J B

Abstract excerpt

The homeobox gene Cdx2, a homologue of the Drosophila gene caudal, has been implicated in the control of cell differentiation in the intestinal epithelium. Recently, we showed that mice in which one allele of the Cdx2 gene had been inactivated by homologous recombination developed multiple intestinal polyp-like lesions that did not express Cdx2 and that contained areas of squamous metaplasia in the form of...

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Identifiers

PMID: 10377412
DOI: 10.1073/pnas.96.13.7318
PMCID: PMC22083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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