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Article

Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium

1 Jan 2001

Abstract excerpt

Caudal-related homeobox (Cdx) proteins play an important role in development and differentiation of the intestinal epithelium. Using cDNA differential display, we identified clusterin as a prominently induced gene in a Cdx2-regulated cellular model of intestinal differentiation. Transfection experiments and DNA-protein interaction assays showed that clusterin is an immediate downstream target gene for Cdx...

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PMID: 11123208
DOI: 10.1152/ajpgi.2001.280.1.g149

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