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Article

PDX-1 Induces Differentiation of Intestinal Epithelioid IEC-6 Into Insulin-Producing Cells

1 Aug 2002

Abstract excerpt

A homeodomain containing transcription factor PDX-1 can induce beta-cell-specific gene expressions in some non-beta-cells and may therefore be useful for future diabetes gene/cell therapy. Among the potential target organs or tissues for transcription factor-mediated induction of beta-cell-like differentiation are the intestinal epithelial cells. They have certain merits over other tissues and organs in terms of...

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PMID: 12145164
DOI: 10.2337/diabetes.51.8.2505

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PDX-1 Induces Differentiation of Intestinal Epithelioid IEC-6 Into Insulin-Producing CellsPMID 12145164Read ↗

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