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Article

p53 gene deletion and trisomy 12 in hairy cell leukemia and its variant.

Leukemia research - 1 Nov 1999

Vallianatou K, Brito-Babapulle V, Matutes E, Atkinson S, Catovsky D

Abstract excerpt

The deletion or mutation of the p53 tumour suppressor gene on chromosome 17p13 is known to be associated with aggressive disease in several B-cell malignancies. The present study describes the p53 gene status in 20 cases of hairy cell leukemia (HCL) and in 12 cases of its morphological variant (HCL-V) by fluorescence in situ hybridization (FISH). A high incidence of p53 deletion was found in both diseases...

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Share to Chromosomes, Human, Pair 12
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10576509
DOI: 10.1016/s0145-2126(99)00127-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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