Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance.

doi:10.3109/10428199509107891

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Article

Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance.

Leukemia & lymphoma - 1 Oct 1995

Nakai H, Misawa S

Abstract excerpt

We have reviewed all the relevant studies on the loss of the short arm of chromosome 17 (17p) and inactivation of the p53 gene in chronic myelogenous leukemia (CML) in an attempt to clarify their roles in the progression of CML. Loss of a 17p (hemizygous 17p) and p53 inactivation emerged as the d...

Topics

Blast Crisis
Chromosome Aberrations
Chromosome Deletion
Chromosome Disorders
Chromosomes, Human, Pair 17
Genes, p53
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phenotype
Prognosis
Survival Analysis

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