Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protease inhibitor phenotype BsaskatoonM is not associated with emphysema - a 20-year follow-up study.

Canadian respiratory journal - 1 Jan 2000

Jokic R, Fisher K L, Cockcroft D W

Abstract excerpt

OBJECTIVE: To investigate the association between the PiBsaskatoon variant of alpha-1 protease inhibitor (a1 Pi), present in the heterozygous state, and the development of emphysema. DESIGN: Twenty-year follow-up in the third generation of a family with the variant, naturally controlled with regard to both environmental influences and other genetic factors. SETTING: University teaching hospital. POPULATION...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heterozygote

Share to Pedigree

Share to Pulmonary Emphysema

Share to Smoking

Share to Time Factors

Source

Identifiers

PMID: 10572206
DOI: 10.1155/1999/409016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protease inhibitor phenotype BsaskatoonM is not associated with emphysema - a 20-year follow-up study.PMID 10572206Read ↗

SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort.Semantic proximity Read ↗

Identification of a new defective SERPINA1 allele (PI*Zla palma) encoding an alpha-1-antitrypsin with altered glycosylation pattern.Semantic proximity Read ↗

A longitudinal study of alpha1-antitrypsin phenotypes and decline in FEV1 in a community population.Semantic proximity Read ↗

Effect of cigarette smoking on pulmonary function in each phenotype M of alpha-1-protease inhibitor.Semantic proximity Read ↗

COPD in individuals with the PiMZ alpha-1 antitrypsin genotype.Semantic proximity Read ↗

Pulmonary function in children with homozygous alpha1-protease inhibitor deficiency.Semantic proximity Read ↗

Age of SERPINA1 gene PI Z mutation: Swedish and Latvian population analysis.Semantic proximity Read ↗

Distribution of alpha(1)-antitrypsin alleles in patients with bronchiectasis.Semantic proximity Read ↗

Longitudinal lung function study in heterozygous PiMZ phenotype subjects.Semantic proximity Read ↗

The protease inhibitor PI*S allele and COPD: a meta-analysis.Semantic proximity Read ↗

Health status and lung function in the Swedish alpha 1-antitrypsin deficient cohort, identified by neonatal screening, at the age of 37-40 years.Semantic proximity Read ↗

Absence of alpha-1-antitrypsin (Pi Null Bellingham) and the early onset of emphysema.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.