Article
Distribution of alpha(1)-antitrypsin alleles in patients with bronchiectasis.
Chest - 1 Feb 2000
Cuvelier A, Muir J F, Hellot M F, Benhamou D, Martin J P, Bénichou J, Sesboüé R
Abstract excerpt
STUDY OBJECTIVES: Bronchiectasis has been reported in a few patients with homozygous alpha(1)-antitrypsin (AAT) deficiency, but the distribution of AAT alleles among bronchiectatic patients is not known. PATIENTS AND DESIGN: Two hundred two patients, 104 men and 98 women, with a mean age (SD) of 63.7 +/- 15.4 years, had bronchiectasis diagnosed by CT scan alone (n = 178), bronchography with or without CT scan (n...
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