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Article

A longitudinal study of alpha1-antitrypsin phenotypes and decline in FEV1 in a community population.

Chest - 1 May 2003

Silva Graciela E, Sherrill Duane L, Guerra Stefano, Barbee Robert A

Abstract excerpt

BACKGROUND: It is well-known that the homozygous deficiency of alpha(1)-antitrypsin, phenotype PiZZ, is associated with an increased risk of COPD. However, studies evaluating the association between the heterozygous forms of the alpha(1)-antitrypsin phenotype PiMZ and rapid decline in lung functi...

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Source

Identifiers

PMID: 12740258
DOI: 10.1378/chest.123.5.1435

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12740258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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