Effect of cigarette smoking on pulmonary function in each phenotype M of alpha-1-protease inhibitor.

doi:10.1378/chest.107.2.395

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Article

Effect of cigarette smoking on pulmonary function in each phenotype M of alpha-1-protease inhibitor.

Chest - 1 Feb 1995

Matsuse T, Fukuchi Y, Matsui H, Sudo E, Nagase T, Orimo H

Abstract excerpt

Human alpha-1-protease inhibitor (alpha-1-Pi) has been known to be a highly polymorphic protein. We hypothesized that antiprotease activity of each phenotype M of alpha 1-protease inhibitor (PiM) might be different among smokers and that a variation of decrease in pulmonary function for a given a...

Topics

Adult
Alleles
Female
Forced Expiratory Volume
Humans
Isoelectric Focusing
Lung Diseases, Obstructive
Male
Middle Aged
Phenotype
Pulmonary Ventilation
Respiratory Mechanics
Smoking
Vital Capacity
alpha 1-Antitrypsin

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