Article
Effect of cigarette smoking on pulmonary function in each phenotype M of alpha-1-protease inhibitor.
Chest - 1 Feb 1995
Matsuse T, Fukuchi Y, Matsui H, Sudo E, Nagase T, Orimo H
Abstract excerpt
Human alpha-1-protease inhibitor (alpha-1-Pi) has been known to be a highly polymorphic protein. We hypothesized that antiprotease activity of each phenotype M of alpha 1-protease inhibitor (PiM) might be different among smokers and that a variation of decrease in pulmonary function for a given amount of cigarette smoking might be associated with PiM phenotypes. To test this, we investigated the effect of...
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