Article
Free secretory component from cystic fibrosis sputa displays the cystic fibrosis glycosylation phenotype.
American journal of respiratory and critical care medicine - 1 Feb 2004
Marshall Lindsay J, Perks Beatrice, Bodey Kathleen, Suri Ranjan, Bush Andrew, Shute Janis K
Abstract excerpt
Secretory IgA contributes to humoral defense mechanisms against pathogens targeting mucosal surfaces, and secretory component (SC) fulfills multiple roles in this defense. The aims of this study were to quantify total SC and to analyze the form of free SC in sputa from normal subjects, subjects with asthma, and subjects with cystic fibrosis (CF). Significantly higher levels of SC were detected in CF compared with...
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