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Article

Impact of mannose-binding lectin insufficiency on the course of cystic fibrosis: A review and meta-analysis.

Glycobiology - 1 Mar 2011

Chalmers James D, Fleming Gillian B, Hill Adam T, Kilpatrick David C

Abstract excerpt

Mannose-binding lectin (MBL) is an innate immune protein produced by the liver. MBL binds to glycoconjugates containing mannose, fucose or N-acetylglucosamine that are present in a wide variety of bacteria, viruses and fungi. Upon binding, MBL may active the lectin pathway of complement or directly opsonize organisms to enhance phagocytosis. MBL is primarily a serum protein but accumulates in the lung during...

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Age Factors
Burkholderia Infections
Cystic Fibrosis
Genotype
Liver Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mannose-Binding Lectin

Pseudomonas Infections

Respiratory Function Tests

Source

Identifiers

PMID: 21045008
DOI: 10.1093/glycob/cwq161

Genes

CFTR
MBL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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