Article
p53 mutations in basal cell carcinomas arising in routine users of sunscreens.
Photochemistry and photobiology - 1 Nov 1999
Rosenstein B S, Phelps R G, Weinstock M A, Bernstein J L, Gordon M L, Rudikoff D, Kantor I, Shelton R, Lebwohl M G
Abstract excerpt
Sun exposure histories were obtained from a series of patients age 35 or younger following diagnosis and removal of a basal cell carcinoma (BCC). The DNA was extracted from tumor biopsy samples derived from BCC of 10 patients who reported that they did not use sunscreens during youth (age 18 or younger) and 10 patients who routinely employed sunscreens during this age period. Exons 5-9 of the p53 gene were then...
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