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Article

UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma.

Journal of the National Cancer Institute - 1 Apr 1998

Ouhtit A, Nakazawa H, Armstrong B K, Kricker A, Tan E, Yamasaki H, English D R

Abstract excerpt

BACKGROUND: A strong association has been found between skin cancer and exposure to UV radiation. The p53 tumor suppressor gene (also known as TP53), which is frequently mutated in human cancers, is believed to be an early target in UV radiation-associated skin carcinogenesis. We have previously developed a sensitive, polymerase chain reaction-based method capable of detecting and quantifying a UV...

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Identifiers

PMID: 9539248
DOI: 10.1093/jnci/90.7.523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma.PMID 9539248Read ↗

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