Inhibition of UV-induced p53 mutations by sunscreens: implications for skin cancer prevention.

Article

Inhibition of UV-induced p53 mutations by sunscreens: implications for skin cancer prevention.

The journal of investigative dermatology. Symposium proceedings - 1 Aug 1998

Ananthaswamy H N, Loughlin S M, Ullrich S E, Kripke M L

Abstract excerpt

Ultraviolet (UV) radiation is a potent human carcinogen and it induces skin cancer in experimental animals. Recent studies have shown that unique mutations in the p53 tumor suppressor gene contribute to the development of human and mouse UV-induced skin cancers. Such mutations are also found in s...

Topics

Animals
Humans
Mice
Mutation
Skin
Skin Neoplasms
Sunscreening Agents
Tumor Suppressor Protein p53
Ultraviolet Rays

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