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Article

Mutation and methylation status of p53 gene promoter in human breast tumours.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2000

Nayak B K, Das B R

Abstract excerpt

Few reports are available on mutations in the promoter of tumour suppressor genes like p16, WT1 and Rb in cancers. However, the involvement of p53 promoter in cancers is not clearly known. Further, methylation of CpG sites is a major contributor of mutations in several genes. So an attempt has been made to determine the mutation and methylation status of p53 promoter in breast tumours. Results have demonstrated...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 10567880
DOI: 10.1159/000030098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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