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Article

[A study on homozygous deletion, hypermethylation, mutation and expression of p16 gene in human breast cancer].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Apr 1999

Guo S, Liao S, Meng Z, Liu J, Huang M, Wang D, Ding H

Abstract excerpt

OBJECTIVE: To investigate the homozygous deletion (HZD), hypermethylation and mutation of p16 gene in human breast cancer and the relationship between the structural alterations of p16 gene and its expression. METHODS: PCR and PCR-methylation assay with silver staining (PCR-MASS) were used to detect HZD and hypermethylation of p16 gene exon 1 in 60 fresh breast cancers and 24 normal breast tissues adjacent to...

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Share to Cyclin-Dependent Kinase Inhibitor p16
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Deletion

Share to Gene Expression Regulation, Neoplastic

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Share to Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 11869517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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