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Article

Association of mutation and hypermethylation of p21 gene with susceptibility to breast cancer: a study from north India.

Molecular biology reports - 1 May 2014

Akhter Naseem, Akhtar Md Salman, Ahmad Md Margoob, Haque Shafiul, Siddiqui Sarah, Hasan Syed Ikramul, Shukla Nootan K, Husain Syed Akhtar

Abstract excerpt

p21 gene located at chromosome 6p21.2 is a possible tumour suppressor gene involved in the pathogenesis of breast cancer. Both genetic and epigenetic alterations in p21 have been implicated in breast carcinoma. In the present study, our main aim was to study the impact of these two kinds of alterations of p21 gene in Indian female breast cancer patients. A total of 150 female breast cancer patients of north India...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24464128
DOI: 10.1007/s11033-014-3159-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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