Article
Calponin modulates the exclusion of Otx-expressing cells from convergence extension movements.
Nature cell biology - 1 Nov 1999
Morgan R, Hooiveld M H, Pannese M, Dati G, Broders F, Delarue M, Thiery J P, Boncinelli E, Durston A J
Abstract excerpt
Otx2, a vertebrate homologue of the Drosophila orthodenticle gene, coordinates two processes in early embryonic development. Not only does it specify cell fate in the anterior regions of the embryo, it also prevents the cells that express it from participating in the convergence extension movements that shape the rest of the body axis. Here we show that, in Xenopus, this latter function is mediated by XclpH3,...
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