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Article

Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain.

Mechanisms of development - 1 Dec 1997

Suda Y, Matsuo I, Aizawa S

Abstract excerpt

Otx1 and Otx2 genes are mouse cognates of a Drosophila head gap gene orthodenticle. The homozygous mutants have previously indicated that Otx2 is essential to development of structures anterior to rhombomere 3, probably reflecting its expression around the early primitive streak stage. Otx2 mutation also exhibits craniofacial defects by haplo-insufficiency. Affected structures correspond to the most anterior and...

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Identifiers

PMID: 9486536
DOI: 10.1016/s0925-4773(97)00161-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain.PMID 9486536Read ↗

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The role of Otx and Otp genes in brain development.Semantic proximity Read ↗

Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila.Semantic proximity Read ↗

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