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Article

Increased induction of osteopetrosis, but unaltered lymphomagenicity, by murine leukemia virus SL3-3 after mutation of a nuclear factor 1 site in the enhancer.

Journal of virology - 1 Dec 1999

Ethelberg S, Tzschaschel B D, Luz A, Diaz-Cano S J, Pedersen F S, Schmidt J

Abstract excerpt

SL3-3 is a murine leukemia virus which is only weakly bone pathogenic but highly T-cell lymphomagenic. A major pathogenic determinant is the transcriptional enhancer comprising several transcription factor binding sites, among which are three identical sites for nuclear factor 1 (NF1). We have investigated the pathogenic properties of NF1 site enhancer mutants of SL3-3. Two different mutants carrying a 3-bp...

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Share to Enhancer Elements, Genetic
Share to Leukemia Virus, Murine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to NFI Transcription Factors

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Source

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Identifiers

PMID: 10559359
DOI: 10.1128/JVI.73.12.10406-10415.1999
PMCID: PMC113096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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