Stability of AML1 (core) site enhancer mutations in T lymphomas induced by attenuated SL3-3 murine leukemia virus mutants.

doi:10.1128/JVI.71.7.5080-5087.1997

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Article

Stability of AML1 (core) site enhancer mutations in T lymphomas induced by attenuated SL3-3 murine leukemia virus mutants.

Journal of virology - 1 Jul 1997

Amtoft H W, Sørensen A B, Bareil C, Schmidt J, Luz A, Pedersen F S

Abstract excerpt

Murine retrovirus SL3-3 is highly T lymphomagenic. Its pathogenic properties are determined by the transcriptional enhancer of the U3 repeat region which shows preferential activity in T cells. Within the U3 repeats, the major determinant of T-cell specificity has been mapped to binding sites for...

Topics

Animals
Base Sequence
Core Binding Factor Alpha 2 Subunit
DNA, Neoplasm
DNA-Binding Proteins
Enhancer Elements, Genetic
Humans
Leukemia Virus, Murine
Leukemia, Experimental
Lymphoma, T-Cell
Mice
Molecular Sequence Data
Mutation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-myc

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Identifiers

PMID: 9188573
DOI: 10.1128/JVI.71.7.5080-5087.1997
PMCID: PMC191741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9188573-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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