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Article

Replication and pathogenicity of primer binding site mutants of SL3-3 murine leukemia viruses.

Journal of virology - 1 Jul 1999

Lund A H, Schmidt J, Luz A, Sørensen A B, Duch M, Pedersen F S

Abstract excerpt

Retroviral reverse transcription is primed by a cellular tRNA molecule annealed to an 18-bp primer binding site sequence. The sequence of the primer binding site coincides with that of a negatively acting cis element that mediates transcriptional silencing of murine leukemia virus (MLV) in undifferentiated embryonic cells. In this study we test whether SL3-3 MLV can replicate stably using tRNA primers other than...

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Identifiers

PMID: 10364369
DOI: 10.1128/JVI.73.7.6117-6122.1999
PMCID: PMC112678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Replication and pathogenicity of primer binding site mutants of SL3-3 murine leukemia viruses.PMID 10364369Read ↗

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