Article
Triple basepair changes within and adjacent to the conserved YY1 motif upstream of the U3 enhancer repeats of SL3-3 murine leukemia virus cause a small but significant shortening of latency of T-lymphoma induction.
Virology - 1 Sept 2003
Ma Shi Liang, Lovmand Jette, Sørensen Annette Balle, Luz Arne, Schmidt Jörg, Pedersen Finn Skou
Abstract excerpt
A highly conserved sequence upstream of the transcriptional enhancer in the U3 of murine leukemia viruses (MLVs) was reported to mediate negative regulation of their expression. In transient expression studies, negative regulation was reported to be conferred by coexpression of the transcription...
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