Article
Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila.
The Journal of cell biology - 1 Nov 1999
Ray K, Perez S E, Yang Z, Xu J, Ritchings B W, Steller H, Goldstein L S
Abstract excerpt
KLP64D and KLP68D are members of the kinesin-II family of proteins in Drosophila. Immunostaining for KLP68D and ribonucleic acid in situ hybridization for KLP64D demonstrated their preferential expression in cholinergic neurons. KLP68D was also found to accumulate in cholinergic neurons in axonal obstructions caused by the loss of kinesin light chain. Mutations in the KLP64D gene cause uncoordinated sluggish...
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