Article
Kinesin-2 differentially regulates the anterograde axonal transports of acetylcholinesterase and choline acetyltransferase in Drosophila.
Journal of neurobiology - 1 Mar 2006
Baqri Rehan, Charan Rakshita, Schimmelpfeng Kristina, Chavan Swati, Ray Krishanu
Abstract excerpt
Choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) are involved in acetylcholine synthesis and degradation at pre- and postsynaptic compartments, respectively. Here we show that their anterograde transport in Drosophila larval ganglion is microtubule-dependent and occurs in two different time profiles. AChE transport is constitutive while that of ChAT occurs in a brief pulse during third instar...
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