Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kinesin light chains are essential for axonal transport in Drosophila.

The Journal of cell biology - 20 Apr 1998

Gindhart J G, Desai C J, Beushausen S, Zinn K, Goldstein L S

Abstract excerpt

Kinesin is a heterotetramer composed of two 115-kD heavy chains and two 58-kD light chains. The microtubule motor activity of kinesin is performed by the heavy chains, but the functions of the light chains are poorly understood. Mutations were generated in the Drosophila gene Kinesin light chain (Klc), and the phenotypic consequences of loss of Klc function were analyzed at the behavioral and cellular levels....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Drosophila
Share to Genes, Insect

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Nerve Tissue Proteins

Share to Neurons

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 9548722
DOI: 10.1083/jcb.141.2.443
PMCID: PMC2148443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kinesin light chains are essential for axonal transport in Drosophila.PMID 9548722Read ↗

Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila.Semantic proximity Read ↗

Defective kinesin heavy chain behavior in mouse kinesin light chain mutants.Semantic proximity Read ↗

Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis.Semantic proximity Read ↗

Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila.Semantic proximity Read ↗

Role of kinesin-1-based microtubule sliding in Drosophila nervous system development.Semantic proximity Read ↗

Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.Semantic proximity Read ↗

Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis.Semantic proximity Read ↗

A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila.Semantic proximity Read ↗

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport.Semantic proximity Read ↗

New cell biological explanations for kinesin-linked axon degenerationSemantic proximity Read ↗

Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions.Semantic proximity Read ↗

The kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.