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The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways.

Genetics - 1 Nov 1999

Alepuz P M, Matheos D, Cunningham K W, Estruch F

Abstract excerpt

In eukaryotes, control of transcription by extracellular signals involves the translocation to the nucleus of at least one component of the signal transduction pathway. Transport through the nuclear envelope requires the activity of an import or export receptor that interacts with the small GTPase Ran. We have cloned the MSN5 gene of the yeast Saccharomyces cerevisiae that is postulated to encode one of these...

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Identifiers

PMID: 10545454
DOI: 10.1093/genetics/153.3.1219
PMCID: PMC1460834

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