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Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in two-cell Caenorhabditis elegans embryos.

Developmental biology - 15 Nov 1999

Basham S E, Rose L S

Abstract excerpt

The early development of Caenorhabditis elegans embryos is characterized by a series of asymmetric divisions in which the mitotic spindle is repeatedly oriented on the same axis due to a rotation of the nuclear-centrosome complex. To identify genes involved in the control of spindle orientation, we have screened maternal-effect lethal mutants for alterations in cleavage pattern. Here we describe mutations in...

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PMID: 10545235
DOI: 10.1006/dbio.1999.9447

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Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in two-cell Caenorhabditis elegans embryos.PMID 10545235Read ↗

Control of cleavage spindle orientation in Caenorhabditis elegans: the role of the genes par-2 and par-3.Semantic proximity Read ↗

The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote.Semantic proximity Read ↗

The Caenorhabditis elegans par-5 gene encodes a 14-3-3 protein required for cellular asymmetry in the early embryo.Semantic proximity Read ↗

par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.Semantic proximity Read ↗

Dissection of cell division processes in the one cell stage Caenorhabditis elegans embryo by mutational analysis.Semantic proximity Read ↗

PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos.Semantic proximity Read ↗

The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo.Semantic proximity Read ↗

The maternal gene spn-4 encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in early C. elegans embryos.Semantic proximity Read ↗

Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle.Semantic proximity Read ↗

PAR-dependent and geometry-dependent mechanisms of spindle positioning.Semantic proximity Read ↗

Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

SPD-3 is required for spindle alignment in Caenorhabditis elegans embryos and localizes to mitochondria.Semantic proximity Read ↗

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