Article
The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo.
Development (Cambridge, England) - 1 Apr 1998
Rose L S, Kemphues K
Abstract excerpt
The orientation of cell division is a critical aspect of development. In 2-cell C. elegans embryos, the spindle in the posterior cell is aligned along the long axis of the embryo and contributes to the unequal partitioning of cytoplasm, while the spindle in the anterior cell is oriented transvers...
Topics
- Actins
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Division
- Gene Expression Regulation, Developmental
- Helminth Proteins
- Immunohistochemistry
- Microscopy, Phase-Contrast
- Mutation
- Phenotype
- Protein Serine-Threonine Kinases
- Spindle Apparatus