Article
Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle.
Developmental biology - 1 Nov 1990
Kirby C, Kusch M, Kemphues K
Abstract excerpt
A dramatic reorganization of cytoplasm occurs during the first cell cycle in embryos of the nematode, Caenorhabditis elegans. We present here the results of a quantitative study of some of the events during this reorganization in wild-type embryos and in par mutant embryos. The par mutations define a set of genes required for cytoplasmic localization in early embryos. We show that par mutations lead to defects in...
Topics
- Actin Cytoskeleton
- Animals
- Caenorhabditis
- Cell Cycle
- Cell Nucleus
- Cytoplasm
- Microscopy, Fluorescence
- Mutation
- Phenotype