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Article

PAR-dependent and geometry-dependent mechanisms of spindle positioning.

The Journal of cell biology - 17 Mar 2003

Tsou Meng-Fu Bryan, Ku Wei, Hayashi Adam, Rose Lesilee S

Abstract excerpt

During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also affects spindle orientation in some systems, but how intrinsic and extrinsic mechanisms coexist without interfering with each other is unknown. In some asymmetrically dividing cells of the wild-type Caenorhabditis elegans...

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Source

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Identifiers

PMID: 12642612
DOI: 10.1083/jcb.200209079
PMCID: PMC2173762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PAR-dependent and geometry-dependent mechanisms of spindle positioning.PMID 12642612Read ↗

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