Article
Impaired memory retention and decreased long-term potentiation in integrin-associated protein-deficient mice.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Jan 1999
Chang H P, Lindberg F P, Wang H L, Huang A M, Lee E H
Abstract excerpt
Previously, we have demonstrated that integrin-associated protein (IAP) mRNA level is approximately fourfold higher in rats showing good retention performance (600 sec) than rats showing poor retention performance (< 80 sec) in an inhibitory avoidance learning paradigm. In the present study, we have used the gene-targeted IAP-deficient mice to further investigate the role of IAP involved in memory formation and...
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