Mouse models of impaired fear memory exhibit deficits in amygdalar LTP.

doi:10.1002/hipo.20075

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Article

Mouse models of impaired fear memory exhibit deficits in amygdalar LTP.

Hippocampus - 1 Jan 2005

Schimanski Lesley A, Nguyen Peter V

Abstract excerpt

Inbred mouse strains have different genetic backgrounds that can result in impairments of synaptic plasticity and memory. They are valuable models for probing the mechanisms of memory impairments. We examined fear memory in several inbred strains, along with synaptic plasticity that may underlie fear memory. Long-term potentiation (LTP) is a form of activity-dependent synaptic plasticity that is a candidate...

Topics

Amygdala
Animals
Disease Models, Animal
Extinction, Psychological
Fear
Female
Genetic Predisposition to Disease
Hippocampus
Long-Term Potentiation
Memory
Memory Disorders
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Perforant Pathway
Species Specificity
Synaptic Transmission

Source

Open in PubMed

Identifiers

PMID: 15744733
DOI: 10.1002/hipo.20075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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