Article
Hepatitis B virus core promoter mutations in children with multiple anti-HBe/HBeAg reactivations result in enhanced promoter activity.
Journal of medical virology - 1 Dec 1999
Gerner P, Lausch E, Friedt M, Tratzmüller R, Spangenberg C, Wirth S
Abstract excerpt
Sera of two children were examined to determine whether specific hepatitis B virus (HBV) mutants may contribute to anti-hepatitis B e/hepatitis B e antigen (anti-HBe/HBeAg) reactivations during the course of chronic hepatitis B. The full-length HBV genome isolated from sera of patient 1 and the basic core promoter (BCP) from patient 2 were amplified and sequenced before and after several reactivations. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
