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Article

Fulminant hepatitis B associated with a specific insertion in the basal core promoter region of hepatitis B virus DNA after immunosuppressive treatment.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2005

Gérolami René, Henry Mireille, Borentain Patrick, Colson Philippe, Botta Danièle, Tamalet Catherine

Abstract excerpt

We report a case of hepatitis B virus reactivation that occurred after immunosuppressive treatment in a hepatitis B surface antigen-negative patient with detectable antibodies to hepatitis B core antigen and hepatitis B surface antigen. Sequence analysis revealed an 11-bp insertion in the core promoter region of hepatitis virus DNA, creating a novel hepatocyte nuclear factor-1 binding site. This led to enhanced...

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Identifiers

PMID: 15712066
DOI: 10.1086/427146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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