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Article

Mutation Changes in the preC/Core Promoter in HBeAg-Positive Patients With Chronic Hepatitis B During Interferon Therapy.

Medicine - 1 Feb 2016

Geng Yan, Wang Xiangling, Lu Xiaolan, Wu Xiaokang, Xu Nan, Han Lei, Xu Jiru

Abstract excerpt

To study the changes in 3 mutations related with hepatitis B e antigen (HBeAg) in patients with HBeAg-positive chronic hepatitis B (CHB) during interferon therapy.HBeAg seroconversion is a major therapeutic milestone for patients with HBeAg-positive CHB. The precore mutation G1896A and the basal core promoter mutations A1762T/G1764A are 3 important mutations that affect the expression of HBeAg; however, the...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 26844490
DOI: 10.1097/MD.0000000000002657
PMCID: PMC4748907

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