Article
Longitudinal study on mutation profiles of core promoter and precore regions of the hepatitis B virus genome in children.
Pediatric research - 1 Sept 2004
Ni Yen-Hsuan, Chang Mei-Hwei, Hsu Hong-Yuan, Tsuei Daw-Jen
Abstract excerpt
Precore nucleotide 1896 and core promoter mutations may account for hepatitis B e antigen (HBeAg) seroconversion in chronic hepatitis B virus (HBV) infection, yet the mutational profiles of the core promoter are largely unknown in children. An age-matched, case-control study enrolled 110 chronic HBV-infected children, including 55 HBeAg seroconverters and 55 nonseroconverters. Precore and core promoter genes of...
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