Article
Pax6-dependent boundary defines alignment of migrating olfactory cortex neurons via the repulsive activity of ephrin A5.
Development (Cambridge, England) - 1 Apr 2006
Nomura Tadashi, Holmberg Johan, Frisen Jonas, Osumi Noriko
Abstract excerpt
Neuronal migration is a prerequisite event for the establishment of highly ordered neuronal circuits in the developing brain. Here, we report Pax6-dependent alignment of the olfactory cortex neurons in the developing telencephalon. These neurons were generated in the dorsal part of telencephalon, migrated ventrally and stopped at the pallium-subpallium boundary (PSB). In Pax6 mutant rat embryos, however, these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
