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Article

Shape and energetics of a cavity in c-Myb probed by natural and non-natural amino acid mutations.

Journal of molecular biology - 1 Oct 1999

Morii H, Uedaira H, Ogata K, Ishii S, Sarai A

Abstract excerpt

The shape and the energetics of a functional cavity in the R2 subdomain (90-141) of the c-Myb DNA-binding domain were investigated by spectroscopy and thermodynamic analysis. We focused on the valine 103 residue located in front of the cavity. Nine mutants, in which valine 103 was substituted with alanine, 2-aminobutyric acid, norvaline, norleucine, leucine, isoleucine, allo -isoleucine, cyclohexylglycine, and...

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Source

Identifiers

PMID: 10525414
DOI: 10.1006/jmbi.1999.3099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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