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Article

Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence.

Molecular psychiatry - 1 Sept 1999

Comings D E, Gonzalez N, Wu S, Saucier G, Johnson P, Verde R, MacMurray J P

Abstract excerpt

We examined the hypothesis that the dopamine D3 receptor gene (DRD3) is a susceptibility factor for cocaine dependence. The MscI/BalI polymorphism of the DRD3 gene was examined in 47 Caucasian subjects with cocaine dependence and 305 Caucasian controls. Based on prior studies with a range of psychiatric disorders we hypothesized there would be a decrease in the frequency of the 12 genotype in the patient sample...

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Share to Cocaine-Related Disorders
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Receptors, Dopamine D2

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Source

Identifiers

PMID: 10523822
DOI: 10.1038/sj.mp.4000542

Genes

DRD3
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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