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Article

Allelic association of the D2 dopamine receptor gene with cocaine dependence.

Drug and alcohol dependence - 1 Oct 1993

Noble E P, Blum K, Khalsa M E, Ritchie T, Montgomery A, Wood R C, Fitch R J, Ozkaragoz T, Sheridan P J, Anglin M D

Abstract excerpt

The objective of the present study was to examine allelic prevalence of the D2 dopamine receptor (DRD2) gene in male cocaine-dependent (CD) Caucasian (non-Hispanic) subjects and to determine the relationship of DRD2 alleles to family history and selected behavioral measures. The prevalence of the A1 allele in CD subjects (n = 53) was 50.9%. It was significantly higher than either the 16.0% prevalence (P < 10(-4))...

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Source

Identifiers

PMID: 8261891
DOI: 10.1016/0376-8716(93)90113-5

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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