Article
Dopamine D3 receptor gene variants and substance abuse in schizophrenia.
Molecular psychiatry - 1 Jul 1998
Krebs M O, Sautel F, Bourdel M C, Sokoloff P, Schwartz J C, Olié J P, Lôo H, Poirier M F
Abstract excerpt
In an association study of the Bal I polymorphism in the dopamine D3 receptor (DRD3) gene in a French Caucasian population, global comparison of patients with schizophrenia (n = 89, DSM-III-R criteria) and controls (n = 52) led to non-significant differences. However, the homozygosity was significantly more frequent in schizophrenic patients with lifetime substance abuse comorbidity (n = 36) as compared to...
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