Article
Dopamine D3 receptor gene variants and substance abuse in schizophrenia.
Molecular psychiatry - 1 Jul 1998
Krebs M O, Sautel F, Bourdel M C, Sokoloff P, Schwartz J C, Olié J P, Lôo H, Poirier M F
Abstract excerpt
In an association study of the Bal I polymorphism in the dopamine D3 receptor (DRD3) gene in a French Caucasian population, global comparison of patients with schizophrenia (n = 89, DSM-III-R criteria) and controls (n = 52) led to non-significant differences. However, the homozygosity was signifi...
Topics
- Comorbidity
- Deoxyribonucleases, Type II Site-Specific
- Female
- France
- Genetic Variation
- Genotype
- Homozygote
- Humans
- Male
- Polymorphism, Restriction Fragment Length
- Psychotic Disorders
- Psychotropic Drugs