Article
The activated type 1-polarized CD8(+) T cell population isolated from an effector site contains cells with flexible cytokine profiles.
The Journal of experimental medicine - 18 Oct 1999
Doyle A G, Buttigieg K, Groves P, Johnson B J, Kelso A
Abstract excerpt
The capacity of activated T cells to alter their cytokine expression profiles after migration into an effector site has not previously been defined. We addressed this issue by paired daughter analysis of a type 1-polarized CD8(+) effector T cell population freshly isolated from lung parenchyma of influenza virus-infected mice. Single T cells were activated to divide in vitro; individual daughter cells were then...
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