Article
Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 1993
Hou S, Doherty P C
Abstract excerpt
Patterns of LECAM-1 and CD45RB expression have been analysed for mediastinal lymph node (MLN) and bronchoalveolar lavage (BAL) populations from C57BL/6J mice with primary Sendai virus pneumonia. The findings indicate that virus-specific CD8+ CTL precursors differentiate in the regional lymph node and become effector CTL after localization to the virus-infected respiratory tract. Relatively few of the MLN CD8+ T...
Topics
- Animals
- CD8 Antigens
- Cell Adhesion Molecules
- Chick Embryo
- Female
- Hematopoietic Stem Cells
- L-Selectin
- Leukocyte Common Antigens
- Lung
- Lymph Nodes
- Mice
