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Article

Polarized cytokine release from airway epithelium differentially influences macrophage phenotype.

Molecular immunology - 1 Apr 2021

Skronska-Wasek W, Durlanik S, Garnett J P, Pflanz S

Abstract excerpt

Epithelial cells and macrophages represent two major cell populations in the lung. They reside in physical proximity and are influenced by inhaled substances, microbial- and host-derived factors, as well as by crosstalk between each other. Here, we report the first systematic study to compare the effects of apical and basolateral secretomes from primary human small airway epithelial cells (SAEC) on human...

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PMID: 33588245
DOI: 10.1016/j.molimm.2021.01.029

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