Article
Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2008
Shi Guangpu, Cox Catherine A, Vistica Barbara P, Tan Cuiyan, Wawrousek Eric F, Gery Igal
Abstract excerpt
Th1 and Th17 cells are characterized by their expression of IFN-gamma or IL-17, respectively. The finding of Th cells producing both IL-17 and IFN-gamma suggested, however, that certain Th cells may modify their selective cytokine expression. In this study, we examined changes in cytokine expression in an experimental system in which polarized Th1 or Th17 cells specific against hen egg lysozyme induce ocular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.