Article
Delayed transfection of DNA after riboflavin mediated photosensitization increases G:C to C:G transversions of supF gene in Escherichia coli mutY strain.
Mutation research - 15 Sept 1999
Takimoto K, Tano K, Hashimoto M, Hori M, Akasaka S, Utsumi H
Abstract excerpt
We have previously reported that the majority of base substitution mutations of the Escherichia coli supF gene induced by riboflavin mediated photosensitization were G:C to C:G changes, in addition to G:C to T:A changes which were probably caused by 8-hydroxyguanine (oh(8)Gua), in wild type and mutM mutator mutant strains. This implies that lesions other than oh(8)Gua are produced by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.